Georgia running back Chauncey Bowens, who leads the No. 2 Bulldogs with six rushing touchdowns in five games, will miss Saturday's game at No. 6 Alabama.
Bowens' absence removes Georgia's leading scorer on the ground heading into a high-stakes matchup against a top-10 opponent.
Meanwhile, Nate Frazier is poised to return after missing most of the past two games due to injury.
Frazier's potential return provides Georgia with a experienced backup option in the backfield as they prepare to face Alabama's defense.
The Bulldogs enter the game ranked No. 2 nationally, while Alabama is ranked No. 6 in the latest standings.
Georgia's rushing attack has been a key component of their success early in the season, with Bowens accounting for half of the team's rushing touchdowns through five games.
Alabama's defense has allowed just over 100 rushing yards per game this season, ranking among the best in the country against the run.
The outcome of the game could have significant implications for College Football Playoff positioning, given both teams' high rankings and SEC standings.
No further details about the nature of Bowens' injury or Frazier's specific condition were provided in the reporting.
ESPN's reporting did not indicate whether Bowens' absence is expected to extend beyond the Alabama game.
This article synthesizes reporting from ESPN. Top story: "Georgia's Chauncey Bowens out vs. Alabama; Nate Frazier off injury report" (ESPN).